Cosby’s lawyers are expected to pressure Judge Steven O’Neill to step aside because they say his wife is a social worker who has described herself as an “advocate for assault victims.”
They lost a bid to overturn his ruling allowing up to five additional accusers to testify.
O’Neill presided over Cosby’s first trial, which ended in a hung jury last year. The retrial could be delayed indefinitely if he bows out.
Jury selection is scheduled to begin Monday.